Adverse Drug Reactions due to Anti TB Treatment
What are the adverse drug reactions which may occur due to anti TB treatment?
Anti TB treatment is from at least 6 months for drug sensitive tuberculosis to up to 18-20 months for multi drug resistant and extensive drug resistant tuberculosis.
Some of the common side effects are as follows
- 1. Gastritis and pain in abdomen
- 2. Nausea and vomiting
- 3. Skin rashes
- 4. Giddiness
- 5. Pins & needle sensation in hands and feet (Tingling / Numbness)
- 6. Skin rashes and/or tanning of skin
- 7. Depression
- 8. Hypothyroidism
- 9. Blurred vision
- 10. Palpitation
What are the tests / work up that may be required in case of adverse drug reaction due to ATT?
- 1. Complete blood counts
- 2. Liver function tests
- 3. Renal function test
- 4. Thyroid function evaluation
- 5. Electrocardiogram – ECG
- 6. Nerve conduction study – NCV6
- 7. Fundoscopy & Color vision (Eyes evaluation)
- 8. Audiomentry (ENT evaluation)
- 9. Psychiatrist evaluation
How to manage these adverse drug reactions?
- 1. Visit your doctor if you are facing these adverse effects
- 2. Do not stop anti TB medicine on your own
- 3. Your doctor may advice some medicine to reduce adverse effects
- 4. Some anti TB medicine can be taken with food or at time interval or at reduced dosage to avoid / reduce adverse effects.
Which are the side effects that require immediate attention to higher center?
Which patients are more prone to develop to develop these ADRs?
- 1. Consume alcohol
- 2. TB with HIV
- 3. Elderly TB patients
- 4. Anemic
- 5. Taking medicines irregularly
- 6. Suffering from other diseases
- 7. Taking other medicines.
Consult your doctor to avoid drug interaction if you are taking other medicines.